What is an important sign of neonatal sepsis?

Temperature instability is a critical sign of neonatal sepsis because it indicates the infant's inability to maintain normal body temperature in response to an infection. Neonates, especially those who are preterm or have a weakened immune system, can experience fluctuations in temperature, either presenting with hypothermia or fever. This instability often signifies that the infant's body is struggling to combat an infection, which could lead to sepsis, a serious and potentially life-threatening condition.

Monitoring temperature in neonates is essential. A significant deviation from the normal range can prompt further investigation and swift medical intervention to address potential infections. The other signs, while they could be associated with other conditions or mild infections, do not have the same urgent clinical significance as temperature instability in the context of evaluating for sepsis.